Drug Uses
Allegra is indicated for the relief of symptoms associated with seasonal allergic rhinitis in adults and children 6 years of age and older. Symptoms treated effectively were sneezing, rhinorrhea, itchy nose/palate/throat, itchy/watery/red eyes.
How Taken
Allegra is formulated as a capsule or tablet for oral administration. Allegra is usually taken twice a day, in the morning and the evening. Follow your doctor's instructions. Take each dose with a full glass of water.
Warnings/Precautions
Do not take Allegra if you have ever had an allergic reaction to it.
Before taking this medication, tell your doctor if you have any serious illness such as heart, kidney, or liver disease. You may require a dosage adjustment or special monitoring during treatment if you have other illnesses.
Allegra is in the FDA pregnancy category C. This means that it is not known whether Allegra will harm an unborn baby. Do not take this medication without first talking to your doctor if you are pregnant.
It is also not known whether Allegra passes into breast milk. Do not take Allegra without first talking to your doctor if you are breast-feeding a baby.
Allegra is not approved for use by children younger than 6 years of age.
Missed Dose
If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not "double-up" the dose to catch up.
Possible Side Effects
Stop taking Allegra and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives).
Allergic reactions occur only rarely, and other serious side effects are not likely to occur.
Some less serious side effects may be more likely to occur. Continue to take Allegra and talk to your doctor if you experience nausea or an upset stomach.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.
Storage
Store Allegra capsules and tablets at controlled room temperature 20-25°C (68-77°F). Foil-backed blister packs containing Allegra capsules and all tablet packaging should be protected from excessive moisture.
Overdose
Symptoms and signs of Allegra overdose are: dizziness, drowsiness, and dry mouth. Seek emergency medical attention.
More Information
Tell your doctor of all nonprescription and prescription medication you may use, especially: MAO inhibitors, certain blood pressure drugs, digoxin, and all adrenaline-like drugs. Report other drugs which affect the heart rhythm. Ask your doctor or pharmacist for more details. Check the labels carefully on all nonprescription products, such as cough-and-cold medicines that contain antihistamines and decongestants. Consult your pharmacist. Do not take Allegra for several days before any allergy testing since test results can be affected. Do not start or stop any medicine without doctor or pharmacist approval.
Disclaimer
This drug information is for your information purposes only, it is not intended that this information covers all uses, directions, drug interactions, precautions, or adverse effects of your medication. This is only general information, and should not be relied on for any purpose. It should not be construed as containing specific instructions for any particular patient. We disclaim all responsibility for the accuracy and reliability of this information, and/or any consequences arising from the use of this information, including damage or adverse consequences to persons or property, however such damages or consequences arise. No warranty, either expressed or implied, is made in regards to this information.
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"It has long been debated whether people who develop asthma have a genetic propensity to develop allergies, or atopy," said Darryl C. Zeldin, M.D., a senior investigator at the National Institute of Environmental Health Sciences (NIEHS). "This new research shows that 56.3 percent of asthma cases are attributed to atopy." Atopy is a condition that results from gene-environment interactions and can be measured by a positive skin test to allergens (or allergy causing substances in the environment).
The study, in the Journal of Allergy and Clinical Immunology, was conducted by researchers at the National Institute of Environmental Health Sciences (NIEHS) and the National Institute of Allergy and Infectious Diseases, both parts of the NIH. The data come from the Third National Health and Nutrition Examination Survey (NHANES III), a nationally representative sample of the population of the United States.
"Sensitization to cat appears to be a strong risk factor for asthma in this study," said Zeldin. Zeldin and his co-authors, however, point out that some research shows that exposure to cats, particularly early in life, may be a protective factor. "We are not advocating parents get rid of pets, but if you suspect that you or your child might have cat allergies or get asthmatic-like symptoms, you should consult with a physician about the best course of action for your family," added Zeldin.
The NIH researchers looked at skin test data for ten allergens. A positive skin test reaction to cat allergens accounted for 29.3 percent of the asthma cases, followed by the fungus Alternaria at 21.1 percent and white oak at 20.9 percent. "Each of 10 allergen-specific skin tests was strongly associated with asthma; however, after adjustment by a variety of subject characteristics and all the allergens, only skin tests to cat, Alternaria and white oak were independently and positively associated with asthma," said Peter Gergen, M.D., M.P.H, of NIAID's Division of Allergy, Immunology and Transplantation, a co-author on the paper.
Other allergens tested include: Ragweed, dustmites, Russian thistle, Bermuda grass, peanuts, perennial rye and german cockroach. Approximately 10,500 individuals participated in the skin testing. During these tests, skin was exposed to allergy-causing substances (allergens) and a positive test was determined by the size of the reaction on the skin.
"This study tells us that allergy is a major factor in asthma," Gergen said. "But this study also tells us is that there are many people who get asthma who don't have allergies. We need to do more research to understand what is causing the asthma that is not related to allergies."
"This study confirms that the environment plays a major role in the development of asthma," said Zeldin. "Given the complexity of this disease it won't be easy, but if we can prevent, block or reverse atopy, we could reduce a large proportion of asthma cases."
Reference: Arbes SJ, Gergen,PJ Vaughn B, Zeldin DC. Asthma cases attributable to atopy: Results from the Third National Health and Nutrition Examination Survey. Journal of Allergy and Clinical Immunology. September, 2007.
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